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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTPRC All Species: 21.21
Human Site: T1212 Identified Species: 42.42
UniProt: P08575 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P08575 NP_002829.2 1304 147254 T1212 A R P G M V S T F E Q Y Q F L
Chimpanzee Pan troglodytes XP_001141776 1304 147111 T1212 A R P G M V S T F E Q Y Q F L
Rhesus Macaque Macaca mulatta XP_001114682 793 89729 V739 T F C A L S T V L E R V K A E
Dog Lupus familis XP_547374 1251 141725 T1158 A R P G M V P T F E Q Y Q F L
Cat Felis silvestris
Mouse Mus musculus P06800 1291 144386 S1200 A R P G V V C S Y E Q Y Q F L
Rat Rattus norvegicus P04157 1273 143251 S1182 A R P G M V G S F E Q Y Q F L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505908 547 62553 E492 E K I E F D N E V D K P K E D
Chicken Gallus gallus NP_989748 1237 139302 N1182 E D K V E F C N E V E K K D Q
Frog Xenopus laevis NP_001089394 819 92510 V765 T F C A L S T V L E R V K A E
Zebra Danio Brachydanio rerio XP_687562 666 75982 S612 A A T E P A N S T P V P V Q K
Tiger Blowfish Takifugu rubipres NP_001027788 1246 141346 S1173 E R Q G M C P S L E Q Y Q F L
Fruit Fly Dros. melanogaster P16620 1462 167441 K1335 E F Y V T N C K I D D T L K V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 27.9 69.1 N.A. 66.5 65.8 N.A. 32.5 50 28.1 27.8 38.9 25.5 N.A. N.A. N.A.
Protein Similarity: 100 99.2 40.9 78.9 N.A. 76.1 75.8 N.A. 37.5 64.7 41.9 36.8 55.6 42.8 N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 93.3 N.A. 73.3 86.6 N.A. 0 0 6.6 6.6 60 0 N.A. N.A. N.A.
P-Site Similarity: 100 100 33.3 93.3 N.A. 93.3 93.3 N.A. 33.3 13.3 33.3 20 66.6 13.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 50 9 0 17 0 9 0 0 0 0 0 0 0 17 0 % A
% Cys: 0 0 17 0 0 9 25 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 9 0 0 0 17 9 0 0 9 9 % D
% Glu: 34 0 0 17 9 0 0 9 9 67 9 0 0 9 17 % E
% Phe: 0 25 0 0 9 9 0 0 34 0 0 0 0 50 0 % F
% Gly: 0 0 0 50 0 0 9 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 0 0 0 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 9 9 0 0 0 0 9 0 0 9 9 34 9 9 % K
% Leu: 0 0 0 0 17 0 0 0 25 0 0 0 9 0 50 % L
% Met: 0 0 0 0 42 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 17 9 0 0 0 0 0 0 0 % N
% Pro: 0 0 42 0 9 0 17 0 0 9 0 17 0 0 0 % P
% Gln: 0 0 9 0 0 0 0 0 0 0 50 0 50 9 9 % Q
% Arg: 0 50 0 0 0 0 0 0 0 0 17 0 0 0 0 % R
% Ser: 0 0 0 0 0 17 17 34 0 0 0 0 0 0 0 % S
% Thr: 17 0 9 0 9 0 17 25 9 0 0 9 0 0 0 % T
% Val: 0 0 0 17 9 42 0 17 9 9 9 17 9 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 0 9 0 0 50 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _